Market overview
The global kidney transplant rejection biomarker market is worth USD 319 mn in 2026 and is forecast to reach USD 755 mn by 2036, growing at a 9.0% CAGR. United States is the largest country market and Donor-derived cell-free DNA is the largest by biomarker segment.
| Scope | Blood tests that measure donor-derived cell-free DNA and gene signatures to detect rejection of a transplanted kidney without biopsy. |
|---|---|
| Industry | Healthcare |
| Value 2025 | USD 290 mn |
| Value 2026 | USD 319 mn |
| Value 2036 | USD 755 mn |
| CAGR 2026-2036 | 9.0% |
| Volume 2026 | 422 thousand tests |
| Volume 2036 | 1,105 thousand tests |
| Average price 2026 | USD 756 per test |
| Report price | Starts from USD 1,999 |
| Published | November 2026 |
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Kidney Transplant Rejection Biomarker market size and forecast, 2026-2036
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| Year | Market value |
|---|---|
| 2026 | USD 319 mn |
| 2027 | USD 348 mn |
| 2028 | USD 379 mn |
| 2029 | USD 413 mn |
| 2030 | USD 450 mn |
| 2031 | USD 491 mn |
| 2032 | USD 535 mn |
| 2033 | USD 583 mn |
| 2034 | USD 636 mn |
| 2035 | USD 693 mn |
| 2036 | USD 755 mn |
Kidney Transplant Rejection Biomarker market segmentation
By biomarker
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Donor-derived cell-free DNA | 72.0% | 69.8% | USD 230 mn | 8.7% |
| Gene expression profiles | 16.0% | 16.2% | USD 51 mn | 9.2% |
| Urine and protein markers | 12.0% | 14.0% | USD 38 mn | 10.7% |
By timing
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Surveillance of stable patients | 54.0% | 52.8% | USD 172 mn | 8.8% |
| Suspected rejection | 34.0% | 31.8% | USD 108 mn | 8.3% |
| Post-treatment monitoring | 12.0% | 15.4% | USD 38 mn | 11.8% |
By technology platform
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Next-generation sequencing | 42.0% | 44.0% | USD 134 mn | 9.5% |
| PCR and digital PCR | 30.0% | 30.0% | USD 96 mn | 9.0% |
| Microarray | 14.0% | 12.0% | USD 45 mn | 7.3% |
| Immunoassay and mass spectrometry | 14.0% | 14.0% | USD 45 mn | 9.0% |
By end user
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Transplant centres | 54.0% | 50.0% | USD 172 mn | 8.2% |
| Reference laboratories | 34.0% | 36.0% | USD 108 mn | 9.6% |
| Hospitals | 12.0% | 14.0% | USD 38 mn | 10.7% |
By payer
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Medicare | 48.0% | 46.0% | USD 153 mn | 8.5% |
| Commercial insurance | 34.0% | 34.0% | USD 108 mn | 9.0% |
| Self-pay and international | 18.0% | 20.0% | USD 57 mn | 10.2% |
Top 25 countries for kidney transplant rejection biomarker by revenue
Countries are ranked by revenue earned from sales in the country, not by where the product is made. The ten largest hold 98.5% of 2026 revenue and the 25 countries below together hold 99.5%.
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| # | Country | Value 2026 | Share 2026 | Value 2036 | CAGR 2026-36 |
|---|---|---|---|---|---|
| 1 | United States | USD 233 mn | 73.0% | USD 536 mn | 8.7% |
| 2 | Germany | USD 16 mn | 5.0% | USD 40 mn | 9.6% |
| 3 | United Kingdom | USD 13 mn | 4.0% | USD 32 mn | 9.8% |
| 4 | France | USD 11 mn | 3.5% | USD 28 mn | 9.6% |
| 5 | Canada | USD 9.6 mn | 3.0% | USD 24 mn | 9.7% |
| 6 | Spain | USD 8.0 mn | 2.5% | USD 20 mn | 9.8% |
| 7 | Italy | USD 8.0 mn | 2.5% | USD 20 mn | 9.8% |
| 8 | Australia | USD 6.4 mn | 2.0% | USD 16 mn | 9.5% |
| 9 | Netherlands | USD 4.8 mn | 1.5% | USD 12 mn | 9.7% |
| 10 | Brazil | USD 4.8 mn | 1.5% | USD 14 mn | 11.6% |
| 11 | Japan | USD 0.32 mn | 0.1% | USD 0.68 mn | 7.9% |
| 12 | China | USD 0.32 mn | 0.1% | USD 1.1 mn | 12.7% |
| 13 | Switzerland | USD 0.32 mn | 0.1% | USD 0.68 mn | 7.9% |
| 14 | Belgium | USD 0.26 mn | 0.08% | USD 0.60 mn | 9.0% |
| 15 | Sweden | USD 0.26 mn | 0.08% | USD 0.60 mn | 9.0% |
| 16 | South Korea | USD 0.26 mn | 0.08% | USD 0.68 mn | 10.3% |
| 17 | Austria | USD 0.22 mn | 0.07% | USD 0.45 mn | 7.3% |
| 18 | Denmark | USD 0.22 mn | 0.07% | USD 0.45 mn | 7.3% |
| 19 | Israel | USD 0.22 mn | 0.07% | USD 0.45 mn | 7.3% |
| 20 | India | USD 0.16 mn | 0.05% | USD 0.53 mn | 12.7% |
| 21 | Norway | USD 0.16 mn | 0.05% | USD 0.38 mn | 9.0% |
| 22 | Saudi Arabia | USD 0.16 mn | 0.05% | USD 0.45 mn | 11.0% |
| 23 | Turkey | USD 0.16 mn | 0.05% | USD 0.45 mn | 11.0% |
| 24 | Ireland | USD 0.16 mn | 0.05% | USD 0.38 mn | 9.0% |
| 25 | Singapore | USD 0.16 mn | 0.05% | USD 0.38 mn | 9.0% |
| Rest of world | USD 1.4 mn | 0.5% | USD 3.1 mn | 8.0% |
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
Competitive landscape
Group 1: Global leaders
- CareDx
- Natera
- Eurofins Viracor
Group 2: Regional and specialist players
- Oncocyte
- Verici Dx
- Chronix Biomedical
Research methodology
Every figure on this page comes from the research framework that we apply to all of the markets we cover. The 2025 base for the kidney transplant rejection biomarker market is built from the volume sold and the price that buyers pay, and is cross-checked against the size of the wider industry the market belongs to. Where a market can be sized in more than one way, the routes are compared before a figure is set.
The forecast runs year by year from the 2025 base to 2036. Growth in each year reflects demand from the industries that buy the product, adoption of new technology, pricing, regulation and replacement cycles. Volume and price are modelled together, so revenue in each year equals volume multiplied by average price. The 2026 to 2036 compound annual growth rate of 9.0% is calculated from the resulting values.
The market is divided by biomarker, by timing, by technology platform, by end user, by payer. The 25 largest countries are ranked by revenue earned from sales to buyers in each country, not by where the product is made. Segment values and country values add up to the market total in every year, and every report is checked for consistency before it is published.
Companies are placed in three groups: global leaders, regional and specialist players, and emerging and niche players. The groups describe how companies compete in the market. They are not a ranking and they are not market shares.
Our analysts also carry out primary research. Customized reports add interviews with key opinion leaders, such as senior executives, technical specialists and buyers, to test the assumptions behind the numbers for the question being asked.
Frequently asked questions
How big is the kidney transplant rejection biomarker market?
The global kidney transplant rejection biomarker market is estimated at USD 290 mn in 2025 and USD 319 mn in 2026.
How fast will the kidney transplant rejection biomarker market grow?
It is forecast to reach USD 755 mn by 2036, a compound annual growth rate of 9.0% from 2026, an increase of USD 436 mn.
Which country is the largest market for kidney transplant rejection biomarker?
United States is the largest market by revenue at USD 233 mn in 2026, 73.0% of the global total. The three largest countries together hold 82.0%.
Which country is growing fastest?
Among the ten largest markets, Brazil is growing fastest at 11.6% a year from 2026 to 2036.
Which kidney transplant rejection biomarker segment is largest?
In the by biomarker split, Donor-derived cell-free DNA is the largest segment with 72.0% of 2026 revenue.
Who are the leading kidney transplant rejection biomarker companies?
Global leaders include CareDx, Natera, Eurofins Viracor.
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