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Kidney Transplant Rejection Biomarker Market Size, Share and Forecast 2026-2036

The global kidney transplant rejection biomarker market is worth USD 319 mn in 2026 and is forecast to reach USD 755 mn by 2036, growing at a 9.0% CAGR. United States is the largest country market and Donor-derived cell-free DNA is the largest by biomarker segment.

USD 319 mnMarket size 2026
USD 755 mnForecast 2036
9.0%CAGR 2026-2036
United StatesLargest country

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5 segmentation views25 countries2026 to 2036 yearly forecast

Market overview

The global kidney transplant rejection biomarker market is worth USD 319 mn in 2026 and is forecast to reach USD 755 mn by 2036, growing at a 9.0% CAGR. United States is the largest country market and Donor-derived cell-free DNA is the largest by biomarker segment.

ScopeBlood tests that measure donor-derived cell-free DNA and gene signatures to detect rejection of a transplanted kidney without biopsy.
IndustryHealthcare
Value 2025USD 290 mn
Value 2026USD 319 mn
Value 2036USD 755 mn
CAGR 2026-20369.0%
Volume 2026422 thousand tests
Volume 20361,105 thousand tests
Average price 2026USD 756 per test
Report priceStarts from USD 1,999
PublishedNovember 2026

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Kidney Transplant Rejection Biomarker market size and forecast, 2026-2036

Exhibit 1The global kidney transplant rejection biomarker market is forecast to grow from USD 319 mn in 2026 to USD 755 mn by 2036, more than doublingGlobal market value in USD: 2025 base year, 2026 estimate and forecast to 2036. CAGR 2026 to 2036: 9.0%
Kidney Transplant Rejection Biomarker market value, 2025 to 2036Market value by year. 2025: USD 290 mn; 2026: USD 319 mn; 2027: USD 348 mn; 2028: USD 379 mn; 2029: USD 413 mn; 2030: USD 450 mn; 2031: USD 491 mn; 2032: USD 535 mn; 2033: USD 583 mn; 2034: USD 636 mn; 2035: USD 693 mn; 2036: USD 755 mn. Compound annual growth rate 2026 to 2036: 9.0%.2025319 mn2026491 mn2031755 mn20369.0% CAGR

Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.

YearMarket value
2026USD 319 mn
2027USD 348 mn
2028USD 379 mn
2029USD 413 mn
2030USD 450 mn
2031USD 491 mn
2032USD 535 mn
2033USD 583 mn
2034USD 636 mn
2035USD 693 mn
2036USD 755 mn

Kidney Transplant Rejection Biomarker market segmentation

By biomarker

Exhibit 2Donor-derived cell-free DNA is the largest segment by biomarker, with 72.0% of 2026 revenueEstimated share of 2026 global revenue, by biomarker
Kidney Transplant Rejection Biomarker market share by biomarker, 2026Share of 2026 revenue by biomarker. Donor-derived cell-free DNA: 72.0%; Gene expression profiles: 16.0%; Urine and protein markers: 12.0%.Donor-derived cell-free DNA72.0%Gene expression profiles16.0%Urine and protein markers12.0%

Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.

SegmentShare 2026Share 2036Value 2026CAGR 2026-36
Donor-derived cell-free DNA72.0%69.8%USD 230 mn8.7%
Gene expression profiles16.0%16.2%USD 51 mn9.2%
Urine and protein markers12.0%14.0%USD 38 mn10.7%

By timing

Exhibit 3Surveillance of stable patients adds the most revenue by timing, growing from USD 172 mn in 2026 to USD 399 mn by 2036Estimated revenue in USD by timing, 2026 and 2036 forecast
Kidney Transplant Rejection Biomarker market by timing, 2026 and 2036Revenue by timing in 2026 and 2036. Surveillance of stable patients: USD 172 mn in 2026, USD 399 mn in 2036, change +132%; Suspected rejection: USD 108 mn in 2026, USD 240 mn in 2036, change +121%; Post-treatment monitoring: USD 38 mn in 2026, USD 116 mn in 2036, change +204%.20262036 forecastChangeSurveillance of stable patients+132%172 mn399 mnSuspected rejection+121%108 mn240 mnPost-treatment monitoring+204%38 mn116 mn

Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.

SegmentShare 2026Share 2036Value 2026CAGR 2026-36
Surveillance of stable patients54.0%52.8%USD 172 mn8.8%
Suspected rejection34.0%31.8%USD 108 mn8.3%
Post-treatment monitoring12.0%15.4%USD 38 mn11.8%

By technology platform

SegmentShare 2026Share 2036Value 2026CAGR 2026-36
Next-generation sequencing42.0%44.0%USD 134 mn9.5%
PCR and digital PCR30.0%30.0%USD 96 mn9.0%
Microarray14.0%12.0%USD 45 mn7.3%
Immunoassay and mass spectrometry14.0%14.0%USD 45 mn9.0%

By end user

SegmentShare 2026Share 2036Value 2026CAGR 2026-36
Transplant centres54.0%50.0%USD 172 mn8.2%
Reference laboratories34.0%36.0%USD 108 mn9.6%
Hospitals12.0%14.0%USD 38 mn10.7%

By payer

SegmentShare 2026Share 2036Value 2026CAGR 2026-36
Medicare48.0%46.0%USD 153 mn8.5%
Commercial insurance34.0%34.0%USD 108 mn9.0%
Self-pay and international18.0%20.0%USD 57 mn10.2%

Top 25 countries for kidney transplant rejection biomarker by revenue

Countries are ranked by revenue earned from sales in the country, not by where the product is made. The ten largest hold 98.5% of 2026 revenue and the 25 countries below together hold 99.5%.

Exhibit 4United States is the largest country market at USD 233 mn in 2026, and the three largest countries hold 82.0% of global revenueEstimated 2026 revenue in USD and share of the global market, ten largest countries
Kidney Transplant Rejection Biomarker market, ten largest countries in 2026Ten largest countries by 2026 revenue. United States: USD 233 mn, 73.0%; Germany: USD 16 mn, 5.0%; United Kingdom: USD 13 mn, 4.0%; France: USD 11 mn, 3.5%; Canada: USD 9.6 mn, 3.0%; Spain: USD 8.0 mn, 2.5%; Italy: USD 8.0 mn, 2.5%; Australia: USD 6.4 mn, 2.0%; Netherlands: USD 4.8 mn, 1.5%; Brazil: USD 4.8 mn, 1.5%.United States233 mn 73.0%Germany16 mn 5.0%United Kingdom13 mn 4.0%France11 mn 3.5%Canada9.6 mn 3.0%Spain8.0 mn 2.5%Italy8.0 mn 2.5%Australia6.4 mn 2.0%Netherlands4.8 mn 1.5%Brazil4.8 mn 1.5%

Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.

#CountryValue 2026Share 2026Value 2036CAGR 2026-36
1United StatesUSD 233 mn73.0%USD 536 mn8.7%
2GermanyUSD 16 mn5.0%USD 40 mn9.6%
3United KingdomUSD 13 mn4.0%USD 32 mn9.8%
4FranceUSD 11 mn3.5%USD 28 mn9.6%
5CanadaUSD 9.6 mn3.0%USD 24 mn9.7%
6SpainUSD 8.0 mn2.5%USD 20 mn9.8%
7ItalyUSD 8.0 mn2.5%USD 20 mn9.8%
8AustraliaUSD 6.4 mn2.0%USD 16 mn9.5%
9NetherlandsUSD 4.8 mn1.5%USD 12 mn9.7%
10BrazilUSD 4.8 mn1.5%USD 14 mn11.6%
11JapanUSD 0.32 mn0.1%USD 0.68 mn7.9%
12ChinaUSD 0.32 mn0.1%USD 1.1 mn12.7%
13SwitzerlandUSD 0.32 mn0.1%USD 0.68 mn7.9%
14BelgiumUSD 0.26 mn0.08%USD 0.60 mn9.0%
15SwedenUSD 0.26 mn0.08%USD 0.60 mn9.0%
16South KoreaUSD 0.26 mn0.08%USD 0.68 mn10.3%
17AustriaUSD 0.22 mn0.07%USD 0.45 mn7.3%
18DenmarkUSD 0.22 mn0.07%USD 0.45 mn7.3%
19IsraelUSD 0.22 mn0.07%USD 0.45 mn7.3%
20IndiaUSD 0.16 mn0.05%USD 0.53 mn12.7%
21NorwayUSD 0.16 mn0.05%USD 0.38 mn9.0%
22Saudi ArabiaUSD 0.16 mn0.05%USD 0.45 mn11.0%
23TurkeyUSD 0.16 mn0.05%USD 0.45 mn11.0%
24IrelandUSD 0.16 mn0.05%USD 0.38 mn9.0%
25SingaporeUSD 0.16 mn0.05%USD 0.38 mn9.0%
Rest of worldUSD 1.4 mn0.5%USD 3.1 mn8.0%
Exhibit 5United States and Germany account for 75% of the USD 436 mn the market is forecast to add by 2036Forecast revenue added between 2026 and 2036 by country, in USD
Kidney Transplant Rejection Biomarker market, where the growth to 2036 comes fromRevenue added between 2026 and 2036. Market value 2026: USD 319 mn. United States: +USD 303 mn; Germany: +USD 24 mn; United Kingdom: +USD 20 mn; France: +USD 17 mn; Canada: +USD 15 mn; 20 other countries: +USD 56 mn; Rest of world: +USD 1.7 mn. Market value 2036: USD 755 mn.Market value 2026319 mnUnited States+303 mnGermany+24 mnUnited Kingdom+20 mnFrance+17 mnCanada+15 mn20 other countries+56 mnRest of world+1.7 mnMarket value 2036755 mn

Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.

Competitive landscape

Group 1: Global leaders

  • CareDx
  • Natera
  • Eurofins Viracor

Group 2: Regional and specialist players

  • Oncocyte
  • Verici Dx
  • Chronix Biomedical

Research methodology

Every figure on this page comes from the research framework that we apply to all of the markets we cover. The 2025 base for the kidney transplant rejection biomarker market is built from the volume sold and the price that buyers pay, and is cross-checked against the size of the wider industry the market belongs to. Where a market can be sized in more than one way, the routes are compared before a figure is set.

The forecast runs year by year from the 2025 base to 2036. Growth in each year reflects demand from the industries that buy the product, adoption of new technology, pricing, regulation and replacement cycles. Volume and price are modelled together, so revenue in each year equals volume multiplied by average price. The 2026 to 2036 compound annual growth rate of 9.0% is calculated from the resulting values.

The market is divided by biomarker, by timing, by technology platform, by end user, by payer. The 25 largest countries are ranked by revenue earned from sales to buyers in each country, not by where the product is made. Segment values and country values add up to the market total in every year, and every report is checked for consistency before it is published.

Companies are placed in three groups: global leaders, regional and specialist players, and emerging and niche players. The groups describe how companies compete in the market. They are not a ranking and they are not market shares.

Our analysts also carry out primary research. Customized reports add interviews with key opinion leaders, such as senior executives, technical specialists and buyers, to test the assumptions behind the numbers for the question being asked.

Read the full research methodology

Frequently asked questions

How big is the kidney transplant rejection biomarker market?

The global kidney transplant rejection biomarker market is estimated at USD 290 mn in 2025 and USD 319 mn in 2026.

How fast will the kidney transplant rejection biomarker market grow?

It is forecast to reach USD 755 mn by 2036, a compound annual growth rate of 9.0% from 2026, an increase of USD 436 mn.

Which country is the largest market for kidney transplant rejection biomarker?

United States is the largest market by revenue at USD 233 mn in 2026, 73.0% of the global total. The three largest countries together hold 82.0%.

Which country is growing fastest?

Among the ten largest markets, Brazil is growing fastest at 11.6% a year from 2026 to 2036.

Which kidney transplant rejection biomarker segment is largest?

In the by biomarker split, Donor-derived cell-free DNA is the largest segment with 72.0% of 2026 revenue.

Who are the leading kidney transplant rejection biomarker companies?

Global leaders include CareDx, Natera, Eurofins Viracor.

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