Market overview
The global amyotrophic lateral sclerosis gene testing market is worth USD 62 mn in 2026 and is forecast to reach USD 167 mn by 2036, growing at a 10.5% CAGR. United States is the largest country market and Multi-gene ALS panels is the largest by test segment.
| Scope | Genetic tests for motor neurone disease and ALS, covering C9orf72, SOD1, FUS, TARDBP and wider neuromuscular gene panels, run in clinical and research laboratories. |
|---|---|
| Industry | Healthcare |
| Value 2025 | USD 55 mn |
| Value 2026 | USD 62 mn |
| Value 2036 | USD 167 mn |
| CAGR 2026-2036 | 10.5% |
| Volume 2026 | 113 thousand tests |
| Volume 2036 | 340 thousand tests |
| Average price 2026 | USD 544 per test |
| Report price | Starts from USD 1,999 |
| Published | November 2026 |
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Amyotrophic Lateral Sclerosis Gene Testing market size and forecast, 2026-2036
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| Year | Market value |
|---|---|
| 2026 | USD 62 mn |
| 2027 | USD 68 mn |
| 2028 | USD 75 mn |
| 2029 | USD 83 mn |
| 2030 | USD 92 mn |
| 2031 | USD 101 mn |
| 2032 | USD 112 mn |
| 2033 | USD 124 mn |
| 2034 | USD 137 mn |
| 2035 | USD 151 mn |
| 2036 | USD 167 mn |
Amyotrophic Lateral Sclerosis Gene Testing market segmentation
By test
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Single gene tests | 24.0% | 14.5% | USD 15 mn | 5.1% |
| Multi-gene ALS panels | 46.0% | 44.3% | USD 28 mn | 10.1% |
| Exome and genome sequencing | 30.0% | 41.2% | USD 18 mn | 14.1% |
By buyer
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Hospital and neurology clinics | 58.0% | 55.0% | USD 36 mn | 9.9% |
| Research and trial screening | 28.0% | 31.8% | USD 17 mn | 11.9% |
| Direct and family testing | 14.0% | 13.3% | USD 8.6 mn | 9.9% |
By gene target
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| C9orf72 | 38.0% | 37.6% | USD 23 mn | 10.4% |
| SOD1 | 22.0% | 21.8% | USD 14 mn | 10.4% |
| FUS and TARDBP | 18.0% | 17.8% | USD 11 mn | 10.4% |
| Other motor neurone genes | 22.0% | 22.8% | USD 14 mn | 10.9% |
By sample type
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Blood | 78.0% | 76.0% | USD 48 mn | 10.2% |
| Saliva | 14.0% | 16.0% | USD 8.6 mn | 12.0% |
| Cerebrospinal fluid and tissue | 8.0% | 8.0% | USD 4.9 mn | 10.5% |
By laboratory type
| Segment | Share 2026 | Share 2036 | Value 2026 | CAGR 2026-36 |
|---|---|---|---|---|
| Hospital laboratories | 36.0% | 35.0% | USD 22 mn | 10.2% |
| Reference laboratories | 42.0% | 42.0% | USD 26 mn | 10.5% |
| Academic and research laboratories | 22.0% | 23.0% | USD 14 mn | 11.0% |
Top 25 countries for amyotrophic lateral sclerosis gene testing by revenue
Countries are ranked by revenue earned from sales in the country, not by where the product is made. The ten largest hold 96.5% of 2026 revenue and the 25 countries below together hold 99.1%.
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
| # | Country | Value 2026 | Share 2026 | Value 2036 | CAGR 2026-36 |
|---|---|---|---|---|---|
| 1 | United States | USD 32 mn | 52.0% | USD 86 mn | 10.3% |
| 2 | Germany | USD 4.9 mn | 8.0% | USD 13 mn | 10.4% |
| 3 | United Kingdom | USD 4.9 mn | 8.0% | USD 14 mn | 11.3% |
| 4 | Japan | USD 3.7 mn | 6.0% | USD 9.9 mn | 10.3% |
| 5 | France | USD 3.1 mn | 5.0% | USD 8.2 mn | 10.3% |
| 6 | Italy | USD 2.5 mn | 4.0% | USD 6.5 mn | 10.2% |
| 7 | Netherlands | USD 2.5 mn | 4.0% | USD 6.8 mn | 10.8% |
| 8 | Canada | USD 2.2 mn | 3.5% | USD 5.7 mn | 10.2% |
| 9 | Spain | USD 1.9 mn | 3.0% | USD 5.2 mn | 10.9% |
| 10 | Australia | USD 1.9 mn | 3.0% | USD 5.3 mn | 11.2% |
| 11 | China | USD 0.22 mn | 0.3% | USD 0.75 mn | 13.3% |
| 12 | Sweden | USD 0.15 mn | 0.2% | USD 0.38 mn | 9.6% |
| 13 | Switzerland | USD 0.14 mn | 0.2% | USD 0.35 mn | 10.0% |
| 14 | Belgium | USD 0.12 mn | 0.2% | USD 0.32 mn | 9.9% |
| 15 | Denmark | USD 0.12 mn | 0.2% | USD 0.32 mn | 9.9% |
| 16 | South Korea | USD 0.12 mn | 0.2% | USD 0.35 mn | 11.0% |
| 17 | Norway | USD 0.10 mn | 0.2% | USD 0.27 mn | 9.8% |
| 18 | Ireland | USD 92 thousand | 0.1% | USD 0.23 mn | 9.7% |
| 19 | Austria | USD 92 thousand | 0.1% | USD 0.23 mn | 9.7% |
| 20 | Israel | USD 92 thousand | 0.1% | USD 0.27 mn | 11.2% |
| 21 | Brazil | USD 74 thousand | 0.1% | USD 0.25 mn | 13.0% |
| 22 | Finland | USD 74 thousand | 0.1% | USD 0.20 mn | 10.5% |
| 23 | Poland | USD 62 thousand | 0.1% | USD 0.18 mn | 11.6% |
| 24 | Singapore | USD 62 thousand | 0.1% | USD 0.18 mn | 11.6% |
| 25 | Taiwan | USD 62 thousand | 0.1% | USD 0.18 mn | 11.6% |
| Rest of world | USD 0.57 mn | 0.9% | USD 1.9 mn | 12.7% |
Source: Compare Market Research analysis.
© 2026 Compare Market Research. All rights reserved.
Competitive landscape
Group 1: Global leaders
- Labcorp
- Quest Diagnostics
- GeneDx
- Fulgent Genetics
- ARUP Laboratories
- Mayo Clinic Laboratories
Group 2: Regional and specialist players
- Ambry Genetics
- Centogene
- Blueprint Genetics
- PreventionGenetics
- Baylor Genetics
- CeGaT
- Macrogen
- Eurofins
Group 3: Emerging and niche players
- Invitae
- Variantyx
Research methodology
Every figure on this page comes from the research framework that we apply to all of the markets we cover. The 2025 base for the amyotrophic lateral sclerosis gene testing market is built from the volume sold and the price that buyers pay, and is cross-checked against the size of the wider industry the market belongs to. Where a market can be sized in more than one way, the routes are compared before a figure is set.
The forecast runs year by year from the 2025 base to 2036. Growth in each year reflects demand from the industries that buy the product, adoption of new technology, pricing, regulation and replacement cycles. Volume and price are modelled together, so revenue in each year equals volume multiplied by average price. The 2026 to 2036 compound annual growth rate of 10.5% is calculated from the resulting values.
The market is divided by test, by buyer, by gene target, by sample type, by laboratory type. The 25 largest countries are ranked by revenue earned from sales to buyers in each country, not by where the product is made. Segment values and country values add up to the market total in every year, and every report is checked for consistency before it is published.
Companies are placed in three groups: global leaders, regional and specialist players, and emerging and niche players. The groups describe how companies compete in the market. They are not a ranking and they are not market shares.
Our analysts also carry out primary research. Customized reports add interviews with key opinion leaders, such as senior executives, technical specialists and buyers, to test the assumptions behind the numbers for the question being asked.
Frequently asked questions
How big is the amyotrophic lateral sclerosis gene testing market?
The global amyotrophic lateral sclerosis gene testing market is estimated at USD 55 mn in 2025 and USD 62 mn in 2026.
How fast will the amyotrophic lateral sclerosis gene testing market grow?
It is forecast to reach USD 167 mn by 2036, a compound annual growth rate of 10.5% from 2026, an increase of USD 106 mn.
Which country is the largest market for amyotrophic lateral sclerosis gene testing?
United States is the largest market by revenue at USD 32 mn in 2026, 52.0% of the global total. The three largest countries together hold 68.0%.
Which country is growing fastest?
Among the ten largest markets, United Kingdom is growing fastest at 11.3% a year from 2026 to 2036.
Which amyotrophic lateral sclerosis gene testing segment is largest?
In the by test split, Multi-gene ALS panels is the largest segment with 46.0% of 2026 revenue.
Who are the leading amyotrophic lateral sclerosis gene testing companies?
Global leaders include Labcorp, Quest Diagnostics, GeneDx, Fulgent Genetics.
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